Seminar of the Mathematical Modeling and Numerical Analysis Department
The next meeting of the seminar of the Department of Mathematical Modeling and Numerical Analysis will be held on October 5, 2026, Monday, at 2:00 pm, in Room 503 of the Institute of Mathematics and Informatics. A talk on: An ODE model for non-monotone dose response to the PD-L1 blockade in vitro will be delivered by Assoc. Prof. Peter Rashkov (IMI - BAS). Abstract: PD-1 is a cell surface receptor on T cells and B cells that has a role in regulating the body's immune response by promoting self-tolerance. The PD-L1 protein on human cells acts as an immune checkpoint, or a „brake“ that prevents T cells from attacking normal cells by binding to PD-1. Cancer cells, however, express high amounts of PD-L1 in [...]